OsteoGen^® Synthetic Bioactive Resorbable crystals and crystal clusters in 300 to 400μ are an osteoconductive, highly hydrophilic, resorbable, synthetically-derived non-ceramic form of hydroxylapatite, the major mineral component of bone and dental enamel. OsteoGen^®, [Ca5(PO4)3(OH)] is used for the augmentation and repair of periodontal and oral-maxillofacial bone defects.

OsteoGen^® is a highly crystalline pure material, comparable to the natural bone by its physiochemical properties, with NO α/β tricalcium phosphates, amorphous phases, or bone-inhibiting pyro-phosphates found in ceramic HA which is devoid of the hydroxyl group.

Controlled manufacturing produces bone grafting crystals of nearly perfectly-formed clusters bound to a single nucleus and relatively hexagonal-shaped crystals. These clusters intertwine to each other for greater porosity to form a 360º lattice mechanism for the host cell proliferation and integration.

OsteoGen^® is an osteoconductive material in that the highly porous crystalline clusters act as a slowly-resorbing matrix permitting the infiltration of bone-forming cells and the subsequent deposition of host bone. OsteoGen^® non-ceramic crystal clusters are highly hydrophilic, allowing the material to readily absorb medullary blood, and migration or material loss is greatly reduced by controlling excessive bleeding with a gauze.

By x-ray diffraction, OsteoGen^® has been shown to meet and exceed ASTM standards and specifications. OsteoGen^® bone graft by dental x-ray will show as radiolucent on the day of placement in defect sites. Four to six months later, the defect site will be radiopaque depending on vascularity, patient’s age, and quantity of product delivered. In many animal and clinical studies, OsteoGen^® has been shown to control the migration of connective tissue.

Preparation is simple and delivery is easily accomplished with conventional instrumentation or a syringe in a sandy consistency.

Compact product well at the defect site.

OsteoGen bioactive resorbable apatite mimics bone structure to help with bone regeneration during dental bone grafts. These calcium apatite bone-grafting crystals are hydrophilic, meaning they draw in blood to start the regrowth process. These crystals are also bioactive and resorbable, allowing them to react with the patient’s cells and slowly break down into non-harmful components that can be assimilated into the body, making them exceptionally useful when it comes to bone grafts for teeth. OsteoGen crystal clusters are radiolucent on the day of placement. Over time, their structure changes, making them radiopaque in four to six months after placement. This makes it easy to check bone growth, so you know when the area is ready to place an implant.

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