Dr. John West JW17 Instruments


Dr. Ziv Simon

"DoWell is an excellent company and I’m never shy to express this. The only problem is that your instruments don’t BREAK and therefore no need to buy too many kits… I am looking forward to our future collaboration."

Dr. Samuel Lee

DoWell Dental Products carries innovative dental instruments that reduces treatment and morbidity to our patients. I am extremely satisfied with DoWell’s quality, and for their friendly service. Thank you Dowell for being there for us!

Dr. Bianca & Dr. Gary Miller

DoWell Piezo ART instrument are GREAT!

I have purchased and I am using the DoWell Piezo ART instrument for removals and sinus augmentation with great ease and textbook success for my patient’s health, comfort, and their restorative reconstruction.

Dr. Bachle

"I love all of my products from DoWell!!

I love all of my products from DoWell Dental Products. Their quality and customer service always goes beyond my expectations."

Dr. Joel R. Benk

I like Dowell Piezo Art. I really like Dowell's Piezo Art!
Especially their Fissured Osteotomy Piezo Tips.


Skip to product information
1 of 5

S1-Natural Xenograft Bone Substitute

Regular price $89.00
Sale price $89.00 Regular price
Sale Sold out
Shipping calculated at checkout.
In Stock

Secure Checkout with

Payment methods
  • American Express
  • Apple Pay
  • Discover
  • Mastercard
  • Visa

100% Secure Payment


BUY 3 GET 1 FREE!  Only for 0.5CC 

BUY 5 GET 1 FREE!  for 1.0CC & 2.0CC 


User Benefits

  1. Excellent adhesion & fixation 
  2. Rigid Space Maintenance 
  3. Excellent osteoconduction
  4. Easy to manipulate 
  5. Various indications

Intended Use

S1 Dental is a xenograft material derived from bovine cancellous bone for the purpose of securing a space where new bone tissue is formed by filling defects or bony voids of the oral and maxillofacial region due to a surgical injury or a non-surgical injury. 

Direction for Use

The general principles of sterile handling and patient medication must be followed when using S1.

1. When using it, peel off blister Tyvek film. Holding S1 vial firmly, remove the cap. Dispense the granules of S1 into a sterile container.
2. After exposure the bony defect with mucoperiosteal flap, completely remove the granulation tissue and inflammatory tissue.
3. When opening the sterile package, never store remained product.
4. Put saline solution in the bone graft material that has been placed in the sterilized container.
5. Use the recommended weight and amount of saline for successful use.
1) Please keep the following points in mind!
· Please comply with the recommended allowance
· Do not divide the product for multiple uses
· Mix with saline solutions well enough
2) The amount of saline is most important!
· Place S1 in the tray and hydrate the materials with saline
· Please use the recommended amount of saline only.
· Do not soak in saline after shaping for surgery.
3) It is important to knead S1 evenly!
· Knead the dough enough for at least 30 seconds by using hands or tools to form a lumpy shape before using S1.
6. After making the product in a paste form suitable for the defect area, apply it to the surgical site using a dental instrument and press it down.
7. After filling the graft, cover the surgical site with mucoperiosteal flap and should be fixed by sutures. Be sure to completely seal the implantation site to prevent exposure.

(Case 1) Alveolar Ridge Preservation without Membrane

(Case 2)Moldable Augmentaion in Anterior Area

So-Yeun Kim, Materials 2021

Independent research shows S1-XB extract significantly promoted osteoblast differentiation.

S.-J.Park, Advanced Healthcare Materials, 2023

The results of radiography, micro-CT, and histological analysis showed S1-XB effectively regenerated bone, indicated by the increase in newly formed bone and bone microstructure thereby improving bone defect filling in the critical defect model and equivalent to the Bio-Oss.

Su-Hyun Hwang, Materials (Basel). 2023

Independent research shows higher bone regeneration in the defects treated with the S1 compare to the control group and bone graft material was easily moldable with the desired shape during surgery.

Reconstructed three-dimensional (3D) images within the 6 mm region of interest using micro-CT analysis after 8 weeks of healing. (a) Control, (b) S1 (yellow: xenograft materials, red: newly formed bone, scale bars = 6 mm).


1) Discard any unused material after opening. Never reuse!
A.) Do not use if package is opened or damaged or if expiration date has been exceeded.
B.) This product should only be used by trained dentists or oral surgeons.

2. Patients with the following diseases are prohibited.
A.) Patients with osteomyelitis
B.) Patients with severe liver dysfunction
C.) Patients with severe cardiac dysfunction

3.) Side Effect Incompatibility reactions with S1 cannot be totally excluded. Possible complications which may occur with any surgery include swelling at the surgical site, flap sloughing, bleeding, local inflammation, bone loss, infection, or pain.

4.) General precautions
A.) In general, the conditions considered as standard contraindications for bone graft are metabolic diseases, osteoporosis, steroid therapy, autoimmune diseases, nicotinism.
B.) As S1 derived from bovine cancellous bone, S1 must not be given to patients allergic to bovine bone. (Although S1 meets “ISO 10993-10 Test for irritation and skin sensitization”, allergic reaction may occur in someone with S1 sensitivity.)
C.) For bone regeneration, the product is only implantable to bone tissue that is directly connected to living bone tissue and host bone. Experience has shown that movement due to increased physical loads (compression loads) or implantation of implants (2-step procedures) should be avoided until several weeks after insertion of the product. Experiments have shown that the physical loading (compression load) of this product augmented areas is possible after 6 months at the earliest. Implant placement time is determined by the amount of remaining local bone.

5.) Do not use S1 for pregnant or lactating women.
6.) S1 should not be used in patients who are skeletally immature. (<18 years of age of no radiographic evidence of epiphyseal closure) 6. Application notes 1) Do not leave any parenchyma or other soft tissue on the defective area to be implanted.
7.) The defect site and the surgical site must be completely closed.